Gene information
Official symbol GH1
Official full name growth hormone 1
Gene type protein-coding gene
Chromosome17q23.3
Alias symbolGH-N; GHN; GH; hGH-N
Gene familyGrowth hormone family
Resources
Entrez Gene 2688
HGNC HGNC:4261
Ensembl ENSG00000259384
Vega OTTHUMG00000172293
UCSC uc002jdj.4
GO terms: 64 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0005179 hormone activity GO Molecular Functions -33.3562443 33 More
GO:0007167 enzyme-linked receptor protein signaling pathway GO Biological Processes -26.8285253 93 More
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway GO Biological Processes -16.7048742 60 More
GO:0008083 growth factor activity GO Molecular Functions -26.3260872 31 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009991 response to extracellular stimulus GO Biological Processes -42.2178323 102 More
GO:0010827 regulation of glucose transmembrane transport GO Biological Processes -18.4601079 28 More
GO:0010828 positive regulation of glucose transmembrane transport GO Biological Processes -9.82015489 15 More
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -15.9250248 30 More
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -18.2876323 28 More
GO:0021700 developmental maturation GO Biological Processes -12.5205714 23 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031667 response to nutrient levels GO Biological Processes -41.8130555 98 More
GO:0031904 endosome lumen GO Cellular Components -9.27147512 9 More
GO:0032355 response to estradiol GO Biological Processes -15.3711017 31 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0040014 regulation of multicellular organism growth GO Biological Processes -9.11971182 17 More
GO:0040018 positive regulation of multicellular organism growth GO Biological Processes -2.86749174 6 More
GO:0042509 regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.4049069 20 More
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.8380655 19 More
GO:0043405 regulation of MAP kinase activity GO Biological Processes -18.9267681 42 More
GO:0043406 positive regulation of MAP kinase activity GO Biological Processes -13.8261343 18 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway GO Biological Processes -9.31062473 8 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0045927 positive regulation of growth GO Biological Processes -20.3035639 52 More
GO:0046425 regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.5317026 20 More
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.8890337 15 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048638 regulation of developmental growth GO Biological Processes -23.5012496 63 More
GO:0048639 positive regulation of developmental growth GO Biological Processes -14.4198804 35 More
GO:0048799 animal organ maturation GO Biological Processes -4.70812216 5 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051427 hormone receptor binding GO Molecular Functions -9.65736435 9 More
GO:0060348 bone development GO Biological Processes -12.2474877 36 More
GO:0060416 response to growth hormone GO Biological Processes -3.42936731 7 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0070977 bone maturation GO Biological Processes -5.08699974 5 More
GO:0071375 cellular response to peptide hormone stimulus GO Biological Processes -15.9961580 44 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071695 anatomical structure maturation GO Biological Processes -11.1692541 20 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:0071902 positive regulation of protein serine/threonine kinase activity GO Biological Processes -13.5008002 23 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904894 positive regulation of receptor signaling pathway via STAT GO Biological Processes -11.2917234 16 More
KEGG pathways: 5 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04630 JAK-STAT signaling pathway KEGG Pathway -14.4088859 21 More
hsa04935 Growth hormone synthesis, secretion and action KEGG Pathway -2.82078524 13 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
acp-001 TTD view
somavaratan TTD view
Related studies: 4 records
Molecular factor Omics type Application Objective MI type Reference
somatotropin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Ceremuzynski L et al. Pol Med Sci Hist Bull. 1999
somatotropin proteomics myocardial injury[prognosis (bad)] acute myocardial infarction Friberg L et al. Eur Heart J. 2000
somatotropin proteomics major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Ng LL et al. Biomarkers. 2015
somatotropin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Dizdarevic-Hudic L et al. Acta Clin Croat. 2016
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